VAN HELSING is pure cinematic comic book horror and Hugh Jackman knows how to pull it off (X-Men franchise). It's over-the-top and funny, and uses the Catholic Church (to an absurd extreme) and Catholic imagery and theological tradition, much like Nosferatu (the Dracula story is the Christ story in reverse) and other Dracula stories.
It's really a too-long hodge-podge of all the vampire/Frankenstein flicks that have come before - but it was fun. I think there's a commentary in there somewhere on what happens when technology, human life and religion mix. What makes a human being? And who gives life? What's going on with the maternal image?